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GLP-1s account for 23% of first line diabetes therapy in 2025 – up from 3% in 2021 Since 2019, the American Diabetes Association (ADA) has revised its Standards of Care each year to expand the role of GLP-1 receptor agonists and SGLT2 inhibitors as first-line treatments for T2D 2

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They describe reta as a "next-gen" GLP-1 drug, saying the injectable they are taking helped them cut fat and get lean without the muscle wasting that many people experience on Ozempic, Wegovy, Mounjaro, or Zepbound